Status:

RECRUITING

Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate

Lead Sponsor:

Shandong University

Conditions:

Colonic Polyps

Adenomatous Polyps

Eligibility:

All Genders

45-85 years

Phase:

NA

Brief Summary

Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection ra...

Detailed Description

If patients scheduled for colonoscopy meet the inclusion criteria but not the exclusion criteria, participants will be recruited to the study and randomized to one of two groups. Group allocation was ...

Eligibility Criteria

Inclusion

  • Age between 45 and 85 years
  • Patients with a history of colorectal adenoma
  • Patients whose first-degree relatives have a history of colorectal cancer or colorectal adenoma
  • Patients with gastrointestinal symptoms (abdominal pain, bloody stool, chronic diarrhea or constipation, Unexplained anemia or weight loss;
  • Patients with positive Fecal Immunochemical Test

Exclusion

  • Patients with pregnancy, inflammatory bowel disease, familial adenomatosis polyposis, suspected CRC; intestinal obstruction, coagulopathy
  • Patients with aspirin, clopidogrel or other anticoagulants/ antiplatelet drugs intake within 7 days
  • Patents previous colorectal resection
  • Patients with failed cecal intubation
  • Patients with inadequate bowel preparation quality (BBPS≤5)
  • Patients who refuse to participate or to provide informed consent

Key Trial Info

Start Date :

April 8 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2026

Estimated Enrollment :

352 Patients enrolled

Trial Details

Trial ID

NCT06961149

Start Date

April 8 2025

End Date

April 1 2026

Last Update

May 7 2025

Active Locations (1)

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Qilu Hospital of Shandong University

Jinan, Shandong, China, 250012