Status:
RECRUITING
The Effect of Personalized Exercise Interventions for the Prevention of Chemotherapy-induced Peripheral Neuropathy
Lead Sponsor:
Universiteit Antwerpen
Collaborating Sponsors:
University Hospital, Antwerp
Universitaire Ziekenhuizen KU Leuven
Conditions:
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating and common side effect of neurotoxic cancer treatment. The most frequent symptoms include sensory disturbances and weakness in the h...
Detailed Description
The scientific goals of the project are: 1. The primary scientific objective of the study is to determine the effect of a patient-tailored exercise program based on exercise guidelines in oncology on...
Eligibility Criteria
Inclusion
- age above 18 years
- a primary diagnosis of breast, gynaecological or colon cancer, without distant metastasis
- been chemotherapy naïve
- been scheduled for at least 12 weeks of taxane- or platinum-based chemotherapy without other neurotoxic chemotherapy
Exclusion
- life expectancy of less than six months according to the patient's oncologist or designee
- advanced stage of disease
- having a known current neuropathy
- having cognitive or physical limitations that contraindicate participation in a low- to moderate intensity home-based walking and progressive resistance program (determined by the patient's oncologist)
- not able to read and understand Dutch
- not able to provide informed consent
- not able to participate during the entire study period
- pregnancy
Key Trial Info
Start Date :
June 5 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2028
Estimated Enrollment :
206 Patients enrolled
Trial Details
Trial ID
NCT06962579
Start Date
June 5 2025
End Date
November 1 2028
Last Update
July 9 2025
Active Locations (2)
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1
Antwerp University Hospital
Edegem, Belgium, 2650
2
University Hospital Leuven
Leuven, Belgium, 3000