Status:

RECRUITING

Cerebral Large Vessel Occlusion Stroke Multiomics Biosample Cohort

Lead Sponsor:

First Affiliated Hospital of Wannan Medical College

Collaborating Sponsors:

Beijing Tiantan Hospital

The First Affiliated Hospital of Zhengzhou University

Conditions:

Large Vessel Occlusion

Acute Ischemic Stroke

Eligibility:

All Genders

Brief Summary

This multicenter, ambispective cohort study establishes a comprehensive multiomics biobank from five stroke centers, encompassing thrombi, intracranial blood, peripheral arterial/venous blood, and cli...

Detailed Description

This study is a multicenter, ambispective cohort study. Blood clot, peripheral arterial blood, peripheral venous blood, and intracranial blood samples were collected from patients at 5 stroke centers ...

Eligibility Criteria

Inclusion

  • Age over 18 years.
  • Patients with intracranial and extracranial large vessel occlusion ischemic stroke confirmed by cerebrovascular angiography.
  • Availability of complete clinical and follow-up information required for the study.
  • Availability of blood and/or thrombus biological samples.
  • Voluntary written informed consent signed by the patient or their family (1) For retrospectively enrolled patients, a "broad informed consent" was signed at the time of sample collection. Upon enrollment into the cohort, a follow-up phone call was made to confirm the informed consent.
  • (2) For prospectively enrolled patients, informed consent for this study was signed at the time of enrollment by the patient or their family.

Exclusion

  • Patients for whom biological samples cannot be obtained;
  • Patients or their family members who refuse to sign the informed consent form.

Key Trial Info

Start Date :

April 27 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 29 2028

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT06963489

Start Date

April 27 2025

End Date

February 29 2028

Last Update

May 11 2025

Active Locations (5)

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Page 1 of 2 (5 locations)

1

The First Affiliated Hospital of Shihezi University

Wuhu, Anhui, China

2

Baotou Central Hospital

Baotou, Inner Mongolia, China

3

Affiliated Hospital of Shandong University of Traditional Chinese Medicine Hospital

Jinan, Shandong, China

4

The First Affiliated Hospital of zhengzhou University

Henan, Zhengzhou, China

Cerebral Large Vessel Occlusion Stroke Multiomics Biosample Cohort | DecenTrialz