Status:

ENROLLING_BY_INVITATION

Influence of Original Native Aortic Valve Lesion (Stenosis or Steno-insufficiency vs. Insufficiency) on Post-implant Structural Bioprosthetic Degeneration After Aortic Valve Replacement

Lead Sponsor:

Maastricht University Medical Center

Conditions:

Aortic Bioprosthesis Degeneration

Eligibility:

All Genders

18+ years

Brief Summary

All patients undergoing elective aortic valve replacement for stenotic aortic valve replacement or aortic valve regurgitation at our institution from 2012 to 2021 who met the inclusion criteria for th...

Detailed Description

All patients undergoing elective aortic valve replacement for stenotic aortic valve replacement or aortic valve regurgitation at our institution from 2012 to 2021 who met the inclusion criteria for th...

Eligibility Criteria

Inclusion

  • \- Age ≥ 18 years; 9
  • Patients who underwent isolated aortic and mitral valve replacement for stenosis or regurgitation
  • Signed informed consent, inclusive of release of medical information.

Exclusion

  • \- Aortic and mitral valve replacement associated with surgery of ascending aorta/aortic root;
  • Aortic and mitral valve replacement associated with other cardiac valve surgery (apart from arrythmia-related ablation or procedures);
  • Previous cardiac surgery of any kind;
  • Surgery for acute endocarditis
  • Surgery for Type A aortic dissection
  • Participation in another clinical trial that could interfere with the endpoints of this study.
  • Pregnant or breastfeeding at time of screening.

Key Trial Info

Start Date :

January 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

10000 Patients enrolled

Trial Details

Trial ID

NCT06964035

Start Date

January 1 2024

End Date

January 1 2026

Last Update

May 15 2025

Active Locations (1)

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Maastricht UMC+ METC

Maastricht, Maastricht, Netherlands