Status:

RECRUITING

Microplastics and Nanoplastics (MNPs) in Patients With ST-elevation Myocardial Infarction (STEMI)

Lead Sponsor:

Azienda Ospedaliera "Sant'Andrea"

Collaborating Sponsors:

University of Campania Luigi Vanvitelli

Azienda Ospedaliera Universitaria Integrata Verona

Conditions:

ST-elevation Myocardial Infarction (STEMI)

Microplastics

Eligibility:

All Genders

18+ years

Brief Summary

Air pollution and microplastics pose major public health threats. Emerging data have shown that micro- and nanoplastics (MNPs) are ubiquitous environmental pollutants accumulating in human tissues, tr...

Eligibility Criteria

Inclusion

  • All the following inclusion criteria should be fulfilled:
  • Age \> 18 years old;
  • STEMI undergoing urgent invasive coronary angiography;
  • Acute thrombotic coronary occlusion/sub-occlusion (TIMI 0/1);
  • Clinical indication to thromboaspiration;
  • Able to give informed consent.

Exclusion

  • Contraindications to percutaneous coronary intervention;
  • Hemodynamic instability or cardiogenic shock;
  • End-stage chronic kidney disease;
  • Life expectancy \< 1 year due to non-cardiac pathology.

Key Trial Info

Start Date :

April 22 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2027

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT06965023

Start Date

April 22 2025

End Date

December 31 2027

Last Update

May 11 2025

Active Locations (10)

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Page 1 of 3 (10 locations)

1

Sant'Andrea University Hospital

Roma, Rome, Italy, 00189

2

Department of Environmental Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli

Caserta, Italy

3

Division of Cardiology, A.O.R.N. "Sant'Anna e San Sebastiano", Caserta, Italy.

Caserta, Italy

4

Cardiovascular Department, A.O.U. Policlinico "G. Rodolico - San Marco", University of Catania, Catania, Italy.

Catania, Italy