Status:
RECRUITING
To Determine Whether it is Feasible to Treat Patients Requiring Urgent Radiotherapy Diagnosed With Metastatic Cord Compression (MSCC) on the Magnetic Resonance Linear Accelerator (MRL) in a Single Appointment and Compare it to the Standard of Care Radiotherapy Pathway
Lead Sponsor:
The Christie NHS Foundation Trust
Conditions:
Metastatic Spinal Cord Compression
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this clinical trial is to understand whether the Magnetic Resonance Linear Accelerator (MRL) could expedite Radiotherapy treatment for Metastatic Cord Compression (MSCC) by removing the ne...
Detailed Description
Metastatic cord compression occurs in 5-10% of patients with cancer often affected the ends stages of a patient's illness. The benefit of palliation is directly related to the speed of treatment, Nati...
Eligibility Criteria
Inclusion
- Confirmed Diagnosis of MSCC
- Referred for an 8Gy, Single Fraction of Radiotherapy
- 18 years or older.
- Able to give informed consent in writing or verbally.
- Willing to complete patient experience questionnaire
- Willing to have the research team review their case notes for up to 1 year following
Exclusion
- Participant does not have capacity and cannot give informed consent.
- Any evidence of significant clinical disorder or laboratory finding which, in the opinion of the investigator, make it undesirable for the patient to participate in the study.
- Participant is unwilling to allow researchers to access their clinical notes and diagnostic scans.
- Participant is unwilling to complete an experience questionnaire
- The participant cannot speak or understand English.
- Exclusion Criteria MRL arm:
- Any contraindications to MRI identified after MRI safety screening
- Unable to tolerate MRI scanning
- Uncontrolled pain/ poor pain control.
- MSCC in the cervical spine.
- More than one vertebral level of compression
Key Trial Info
Start Date :
November 4 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 4 2028
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT06965101
Start Date
November 4 2025
End Date
November 4 2028
Last Update
December 2 2025
Active Locations (1)
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1
The Christie NHS Foundation Trust
Manchester, United Kingdom, M20 4BX