Status:

RECRUITING

Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy

Lead Sponsor:

Northwell Health

Conditions:

Facet Joint Arthropathy

Pain

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

This single-site, single-arm study evaluates the feasibility, safety, tolerability, and efficacy of trans-arterial embolization (TAE) using Embozene microparticles for treating facetogenic pain due to...

Detailed Description

This is a single site, single-arm study assessing the feasibility, safety, tolerability, and efficacy of trans-arterial embolization for the treatment of facet pain due to facet arthropathy. Osteoarth...

Eligibility Criteria

Inclusion

  • Age 18-85
  • Confirmed diagnosis of spinal facet arthropathy on MRI OR CT
  • Confirmed diagnosis of lumbosacral facetogenic pain based on diagnostic nerve blocks.
  • Failed medical management of pain.
  • Back pain persistent for at least 6 months
  • Pain worse than at least 6/10 on a visual analog pain scale
  • Failed at least one of either intra-articular injections of steroids/ anesthetics or neuro-ablative procedure.
  • Maximum of 2 spinal levels of facetogenic pain in the lumbar and sacral spine (i.e. L4-5 and L5-S1).
  • Modified Rankin Scale 0-2

Exclusion

  • \- Pregnancy
  • History of prior spinal embolization at the target level.
  • History of surgery/ stenting of the aorta at the level of embolization.
  • Severe allergic reaction to iodinated contrast (i.e. anaphylaxis)
  • Creatinine \> 1.5 mg/dl and/or creatinine clearance \< 60 mL/min (except if patients is already on hemodialysis).
  • Modified Rankin Scale \>2
  • Angiographic/ Procedural Exclusion Criterion: Vascular supply to the spinal cord from the vessels supplying the facet joints targeted for embolization.

Key Trial Info

Start Date :

August 12 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06965452

Start Date

August 12 2025

End Date

August 1 2026

Last Update

August 19 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

North Shore University Hospital

Manhasset, New York, United States, 11030