Status:

RECRUITING

Rebound Pain After Peripheral Nerve Blocks in Total Knee Arthroplasty

Lead Sponsor:

Konya City Hospital

Conditions:

Total Knee Arthroplasty

Postoperative Pain

Eligibility:

All Genders

18-70 years

Brief Summary

This prospective observational study aims to determine the incidence and clinical impact of rebound pain after peripheral nerve blocks in patients undergoing total knee arthroplasty. Rebound pain is d...

Eligibility Criteria

Inclusion

  • Age between 18 and 70 years
  • ASA physical status I to III
  • Scheduled for elective unilateral total knee arthroplasty under spinal anesthesia
  • Peripheral nerve block (PNB) planned as part of multimodal analgesia
  • Ability to understand and provide written informed consent
  • Willingness and ability to complete the postoperative pain diary

Exclusion

  • Known allergy or hypersensitivity to local anesthetics
  • Contraindication to regional anesthesia
  • ASA physical status IV or higher
  • Neurological or psychiatric disorders interfering with study participation or pain reporting
  • Use of anticoagulants or presence of coagulopathy
  • Use of medications that may alter pain perception or rebound pain response
  • Local infection at the block site
  • Emergency surgeries
  • Inability or unwillingness to complete the postoperative pain diary or follow-up

Key Trial Info

Start Date :

May 21 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 25 2025

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06966011

Start Date

May 21 2025

End Date

December 25 2025

Last Update

May 22 2025

Active Locations (1)

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Konya City Hospital

Konya, Turkey (Türkiye), 42090