Status:

ENROLLING_BY_INVITATION

Allergy Delabeling in Antibiotic Stewardship - Evaluations

Lead Sponsor:

University of Pennsylvania

Collaborating Sponsors:

University of Utah

Conditions:

Beta Lactam Allergy in Patients With a Hematologic Malignancy

Eligibility:

All Genders

18+ years

Brief Summary

The goal of this RENEW-EVAL project is to understand the potential barriers to implementation of the RENEW intervention into the routine clinical care of patients with a hematological malignancy.

Detailed Description

The RENEW clinical intervention is designed to evaluate the impact of a comprehensive beta lactam (BL) allergy delabeling intervention on clinical outcomes among patients hospitalized with a hematolog...

Eligibility Criteria

Inclusion

  • Patient participants:
  • a diagnosis of a hematologic malignancy (lymphoma, leukemia, myeloma)
  • a prior label applied to their medical record to indicate a beta lactam allergy
  • hospitalized as an inpatient to an oncology service at the time the study is conducted
  • Clinician participants:
  • member of the primary inpatient care team

Exclusion

  • Patient participants:
  • meet one of the exclusionary criteria for the RENEW clinical intervention
  • Clinician participants:
  • no exclusions

Key Trial Info

Start Date :

December 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2029

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06967467

Start Date

December 1 2025

End Date

October 1 2029

Last Update

December 18 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104