Status:
COMPLETED
Comparison of Weaning Parameters and Diaphragm Thickness Changes
Lead Sponsor:
Tarık Durna
Conditions:
Mechanical Ventilation
Weaning Failure
Eligibility:
All Genders
18+ years
Brief Summary
Determining the appropriate timing for mechanical ventilator weaning in intensive care unit patients is critical to avoid complications related to early or late weaning, including weaning failure. Com...
Detailed Description
Study Title: The Relationship between Diaphragm Thickness Changes and Weaning Predictors in Intensive Care Unit Patients on Mechanical Ventilation Background: Mechanical ventilation weaning, or trans...
Eligibility Criteria
Inclusion
- Age: Participants aged 18 years or older.
- Intubation Status: Participants who are intubated and receiving mechanical ventilation for at least 24 hours.
- Glasgow Coma Scale (GCS): Participants with a GCS score of greater than 8 at the time of enrollment.
- Body Mass Index (BMI): Participants with a BMI lower than 35.
- Weaning Suitability: Participants who are being evaluated for weaning from mechanical ventilation based on routine ICU weaning parameters.
- Informed Consent: Participants or their legal representatives must provide informed consent to participate in the study.
Exclusion
- Age: Participants younger than 18 years.
- Neurological or Cognitive Impairments: Participants with neurological or cognitive conditions that may affect the ability to participate in the study or give informed consent.
- Mechanical Ventilation Duration: Participants who have been on mechanical ventilation for less than 24 hours at the time of enrollment.
- Severe Respiratory Conditions: Participants with conditions such as acute respiratory distress syndrome (ARDS) or those requiring higher levels of respiratory support, such as invasive or non-invasive positive pressure ventilation.
- Severe Heart Failure: Participants with severe heart failure or other critical cardiovascular conditions that may interfere with the ability to tolerate weaning procedures.
- Pregnancy: Female participants who are pregnant or breastfeeding.
- Other Contraindications: Any participant for whom diaphragm ultrasound measurements would be technically difficult or clinically inappropriate (e.g., due to anatomical or technical factors).
Key Trial Info
Start Date :
July 15 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 15 2025
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT06967623
Start Date
July 15 2022
End Date
January 15 2025
Last Update
May 13 2025
Active Locations (1)
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1
Namık Kemal University Hospital
Tekirdağ, Turkey (Türkiye), 59020