Status:
COMPLETED
The Effect of Locally Dilvered Ciprofloxacine Loaded Injectable Platelet-rich Fibrin as an Adjunct to Non-surgical Periodontal Therapy on the Gingival Crevicular Level of Interleukin 6
Lead Sponsor:
Suez Canal University
Conditions:
Periodontitis Stage II
Eligibility:
All Genders
30-45 years
Phase:
NA
Brief Summary
Sixty periodontally diseased patients will be enrolled in the study. After the patients are randomly divided into one of three treated groups, group 1 (n=20), SRP only; group 2 (n=20), SRP + i-PRF; an...
Detailed Description
The current randomized, controlled, parallel-design study will be conducted at Suez Canal University's Oral Medicine and Periodontology Department following approval of the study design by the Institu...
Eligibility Criteria
Inclusion
- Inclusion criteria
- The age range of thirty to forty-five
- The participants were diagnosed with stage II grade B periodontitis based on the 2018 classification.
- Participants who have at least two areas with a probing depth (PD) of ≤5 mm and have periodontal disease
- Clinical attachment loss (CAL) values of ≥2 mm or more in participants with periodontal disorders. (Elgendy et al ., 2015)
- Exclusion Criteria:
- Pregnant and lactating women
- Use of immunosuppressive medications, consumption of antibiotics, and any antioxidants and anti-inflammatory agents in the last three months
- A history of periodontal therapy in the preceding one year
- Subjects with hemoglobin levels \< 11 mg/dL
- Subject participating in any other clinical trials
- Insulin-dependent diabetes
Exclusion
Key Trial Info
Start Date :
January 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 7 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06968286
Start Date
January 1 2025
End Date
August 7 2025
Last Update
August 8 2025
Active Locations (1)
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1
Suez canal university
Ismailia, Egypt, 12345