Status:

RECRUITING

FB-CT2 Includes Two Prospective, Multi-centre Studies With a Medical Device in Hospital Settings: a Randomized, Dual-arm, Open-label Pilot Study in Spain, Followed by a Single-arm, Non-randomized, Open-label International Pivotal Study

Lead Sponsor:

Ultrasound-Innovation Medtech, S.L.

Conditions:

Threatened Preterm Labor

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to evaluate the safety and the ability of a clinical investigation device (Cervisense TPTL) to predict the risk of spontaneous preterm birth in pregnant women with s...

Detailed Description

The study titled "Evaluation of the safety and the preterm birth predictive capacity of the clinical investigation device 'Cervisense TPTL': an international clinical study" is designed to assess both...

Eligibility Criteria

Inclusion

  • Female ≥18 years
  • Singleton pregnancy
  • Live fetus, 28w+0d-36w+6d GA
  • Intact membranes
  • Cervical dilatation \<2 cm
  • Signed informed consent
  • Regular uterine contractions (≥8/60 min) (Pivotal only)

Exclusion

  • Latex allergy
  • Prolapsed membranes
  • Fetal malformation
  • Fetal infection
  • Vaginal bleeding (severe or persistent)
  • Cervical cerclage
  • Müllerian anomalies
  • Pessary use
  • Regular uterine contractions (reported by patient) (Pilot only)
  • History of preterm birth or TPTL (Pilot only)
  • Vasa/placenta previa (Pilot only)
  • Gastrointestinal or urinary infections (Pivotal only)

Key Trial Info

Start Date :

May 10 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2027

Estimated Enrollment :

457 Patients enrolled

Trial Details

Trial ID

NCT06968364

Start Date

May 10 2025

End Date

April 1 2027

Last Update

May 13 2025

Active Locations (14)

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Page 1 of 4 (14 locations)

1

H. Universitario de A Coruña

A Coruña, Spain

2

H. Clínic de Barcelona

Barcelona, Spain

3

H. Sant Joan de Déu

Barcelona, Spain

4

H. Vall d'Hebron

Barcelona, Spain