Status:

NOT_YET_RECRUITING

Glucose Levels in Acute Pancreatitis and the Impact of Insulin Depletion and Bacterial Endotoxaemia

Lead Sponsor:

Manchester University NHS Foundation Trust

Conditions:

Pancreatitis, Acute

Hyperglycaemia

Eligibility:

All Genders

18+ years

Brief Summary

There are currently no early predictive biomarkers for severity of acute pancreatitis (AP) that would allow stratification of patients for potential early interventional therapies. Hyperglycaemia is f...

Detailed Description

Acute pancreatitis (AP) is associated with metabolic dysregulation including dysglycaemia which may predict poor clinical outcomes. Continuous glucose monitoring (CGM) offers a novel method for assess...

Eligibility Criteria

Inclusion

  • Age 18 years or over
  • Admission diagnosis of acute pancreatitis (based on Revised Atlanta Criteria)
  • Ability to provide informed consent in English

Exclusion

  • Known diabetes mellitus
  • Use of insulin therapy before admission
  • Pregnancy
  • Contraindications to CGM (e.g., allergy to device adhesive)

Key Trial Info

Start Date :

December 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 30 2026

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06972238

Start Date

December 1 2025

End Date

August 30 2026

Last Update

May 21 2025

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Glucose Levels in Acute Pancreatitis and the Impact of Insulin Depletion and Bacterial Endotoxaemia | DecenTrialz