Status:

RECRUITING

Mindfulness Meditation for Insomnia

Lead Sponsor:

Brigham and Women's Hospital

Collaborating Sponsors:

National Center for Complementary and Integrative Health (NCCIH)

Conditions:

Sleep Initiation and Maintenance Disorders

Insomnia

Eligibility:

All Genders

18+ years

Phase:

PHASE1

PHASE2

Brief Summary

The investigators will conduct a 3-arm, pilot RCT where participants (N=30) will be randomized in a 1:1:1 design to 4 weeks of instructed bedtime MM practice at night (n=10) vs. uninstructed MM (n=10)...

Eligibility Criteria

Inclusion

  • Age 18 years and older;
  • Chronic insomnia (≥ 3 nights/week, for ≥ 3 months), defined by DSM-V or ICSD-3;
  • Have a primary complaint of difficulty falling asleep (sleep-onset insomnia) with self-reported sleep onset latency \>20 min;
  • Insomnia Severity Index score ≥ 15;
  • Speak and understand English;
  • Have a smart device (phone or tablet) for mobile app installation

Exclusion

  • Current diagnosis of sleep disorders other than insomnia (e.g., narcolepsy, restless leg syndrome, REM sleep behavior disorder, etc.);
  • Shift worker or routine night shifts;
  • Women with pregnancy or breastfeeding;
  • Regular (defined as twice a week or more) practice of mind-body interventions;
  • Patients with pace-maker or routinely using cardiovascular medications that have effects on heart rates (i.e., beta-blockers);
  • Neurological disorders (e.g. epilepsy, dementia, stroke, Parkinson's disease, neuroinfections, brain tumors, etc.) or current diagnosis of comorbid psychotic, substance use, and trauma-related disorders;
  • Currently under medications with sleep changing effects (e.g., anxiolytics/benzodiazepines, selective serotonin reuptake inhibitors, hypnotics, etc.);
  • Hearing impairment or loss. Participants will be asked to report any medication for at least 2 weeks prior to study onset and during the study period.

Key Trial Info

Start Date :

December 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 29 2028

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06972303

Start Date

December 1 2025

End Date

December 29 2028

Last Update

December 11 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02215

Mindfulness Meditation for Insomnia | DecenTrialz