Status:
RECRUITING
Xiangya Cardiopulmonary Health and Disease Cohort
Lead Sponsor:
Xiangya Hospital of Central South University
Conditions:
Respiratory Function Tests，Heart Function Tests
Cardiopulmonary Function
Eligibility:
All Genders
Brief Summary
Xiangya Cardiopulmonary Health and Disease Cohort (XY-CPHDC) is a non-intervention study grounded in real-world data. It is designed as a bidrectional clinical cohort combined retrospective and prospe...
Detailed Description
1.2.1 Study objective 1. Construct a cardiopulmonary holistic assessment cohort covering the full range of resting-exercise-sleep scenarios and encompassing non-cardiopulmonary disease-- cardiopulmon...
Eligibility Criteria
Inclusion
- I1 Inclusion and exclusion criteria for retrospective cohorts 1) Inclusion criteria:
- Patients were either treated or hospitalized in the physical examination center, outpatient and emergency clinic in the Xiangya Hospital of Central South University from January 2010 to April 2025.
- Completion of cardiac function (e.g., echocardiography) and pulmonary function (e.g., pulmonary function test) assessment, with an interval of no more than 1 year between the two.
- Those who had complete clinical diagnostic and therapeutic information (e.g., medical history, medication records, laboratory test results, imaging reports) except for the cardiopulmonary function test report.
- 2)Exclusion criteria
- Patients with complete loss of cardiopulmonary function test reports or key data (e.g., VO2peak, FEV1/FVC, LVEF).
- Patients with loss of key clinical diagnostic and treatment data (e.g., medical history, medication records, laboratory test results).
- 1.2 Inclusion and exclusion criteria for prospective cohort
- 1）Inclusion criteria
- Patients who have been included in the retrospective cohort.
- Voluntarily signed informed consent form to participate in long-term follow-up for ≥3 years.
- Able to complete the baseline assessment of the prospective cohort (including cardiopulmonary function retesting, questionnaires, etc.).
- Stable conditions for follow-up (e.g., living in the local area, available valid contact information, no plans to move in the short term or go out for a long period of time).
- 2\) Exclusion Criteria.
- Patients who have been excluded from the retrospective cohort or for whom key data are missing.
- With severe cognitive impairment, psychiatric disease or verbal communication disorder, unable to cooperate with follow-up and data collection.
- Expected survival time \<3 years (e.g., advanced malignancy, end-stage cardiopulmonary failure, etc.).
- Incomplete cardiopulmonary function or other clinical data during the baseline assessment.
- Those who plan to participate in other interventional clinical trials that may interfere with the assessment of cardiopulmonary function.
Exclusion
Key Trial Info
Start Date :
June 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2035
Estimated Enrollment :
30000 Patients enrolled
Trial Details
Trial ID
NCT06972784
Start Date
June 1 2025
End Date
December 1 2035
Last Update
July 2 2025
Active Locations (1)
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1
Xiangya Hospital, Central South University Affiliated
Changsha, Hunan, China, 457500