Status:
RECRUITING
Blood Flow Restriction and Transcutaneous Electrical Nerve Stimulation on Motor Function in Stroke
Lead Sponsor:
The Hong Kong Polytechnic University
Conditions:
Chronic Stroke
Eligibility:
All Genders
50-80 years
Phase:
NA
Brief Summary
Stroke commonly results in persistent leg impairments that limit mobility and reduce quality of life. This study investigates whether combining low-intensity resistance training with blood flow restri...
Detailed Description
Stroke often leads to persistent lower-limb impairments, limiting functional recovery and quality of life. Low-intensity resistance training with blood flow restriction (LIRT-BFR) has shown promise in...
Eligibility Criteria
Inclusion
- are between 50 and 80 years of age;
- have had a single stroke more than 6 months and less than 15 years;
- have at least 5 degrees of active ankle dorsiflexion in the antigravity position;
- are able to walk 10 m independently, with or without a walking aid;
- are able to score 6 or higher out of 10 on the abbreviated mental test;
- have no skin allergies (e.g. redness or itchiness after application of the electrical stimulation pads) to electrical stimulation or electrodes;
- are able to follow instructions and give informed consent.
Exclusion
- presence of other comorbidities like varicose veins, peripheral neuropathy, cancer, musculoskeletal injury, lower limb peripheral edema, post-surgical swelling, open wounds, or on a medication that increases blood clotting risk;
- resting blood pressure ≥ 160/100 mmHg even after taking medications, cardiovascular comorbidity, heart failure, unstable angina, by-pass surgery, a pacemaker;
- administration of botulinum toxin in the lower limb at least 6 months prior to training;
- history of epilepsy, cochlear implants, any type of deep brain stimulator and metal implants in the head or neck;
- currently not participating in resistance training or high-intensity or long duration cardiovascular exercise;
- lack the ability to feel pain (because of paralysis), or other subjects who cannot complain of discomfort.
Key Trial Info
Start Date :
September 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06973590
Start Date
September 1 2024
End Date
December 31 2026
Last Update
May 15 2025
Active Locations (1)
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1
The Hong Kong Polytechnic University
Hong Kong, Hong Kong