Status:
NOT_YET_RECRUITING
Exposure to Persistent Organic Pollutants and Severity of Endometriosis in the ComPaRe-Endometriosis Cohort
Lead Sponsor:
Institut National de la Santé Et de la Recherche Médicale, France
Conditions:
Endometriosis
Eligibility:
All Genders
18+ years
Brief Summary
Endometriosis is a chronic inflammatory disease affecting \~10% of women of childbearing age. It is characterized by the presence of endometrial-like tissue outside the uterus, causing lesions and adh...
Eligibility Criteria
Inclusion
- ComPaRe participants ⩾ 18 years old. All ComPaRe participants are at least 18 years of age, so our research participants will all be adults.
- Having declared in ComPaRe that they had endometriosis
- Living in the Ile-de-France region (departments 75, 77, 78, 91, 92, 93, 94 or 95);
- Have given electronic consent stating: "By checking this box, I agree to be solicited for research outside ComPaRe"; This criterion is collected at the time of ComPaRe registration, when consent is collected. Participants can withdraw this consent at any time on their secure personal online account on the ComPaRe platform.
- Aged ≤ 45 years to avoid including premenopausal or menopausal women;
- In possession of MRI images used to diagnose their endometriosis (CD-ROM) that are no more than 5 years old;
- Enrolled in or benefiting from a social security scheme.
Exclusion
- \- People with contraindications to blood sampling will not be included in this research:
- Known severe anemia
- Hemophilia/coagulation disorders/anticoagulant use
- People with HIV, HBV or HCV will not be included in this study due to the risk of BSE (Blood Exposure Accident).
- Based on factors that may disrupt lipid dynamics and lipid pollutants, the following individuals will not be included:
- Pregnant and breast-feeding women
- People suffering from any of the following diseases:
- Cancer
- Morbid obesity (BMI\>40)
- Non-alcoholic steatohepatitis (NASH)
- Persons under court protection/guardianship/guardianship will not be able to participate in this research.
Key Trial Info
Start Date :
December 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
650 Patients enrolled
Trial Details
Trial ID
NCT06973603
Start Date
December 1 2025
End Date
September 1 2026
Last Update
September 3 2025
Active Locations (1)
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1
Hôpital Paris Saint Joseph
Paris, France, 75014