Status:
NOT_YET_RECRUITING
Explore the Therapeutic Effect of Theta Burst Stimulation on Emotion Regulation in Autism With Minimally Verbal Ability or Intellectual Disability
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Autism Spectrum Disorder
Minimally Verbal Ability
Eligibility:
All Genders
8-30 years
Phase:
NA
Brief Summary
The investigator would like to investigate the impact of theta-burst stimulation over left DLPFC in autism with minimally verbal ability or intellectual disability
Eligibility Criteria
Inclusion
- Diagnosis of autism spectrum disorder, confirmed by DSM-5.
- Individuals with minimal verbal ability or intellectual disability (FSIQ \< 70).
Exclusion
- Current or past severe neurological disorders, such as epilepsy, or significant visual or hearing impairments.
- Current or past severe systemic diseases, such as cardiovascular disease, diabetes, or multiple sclerosis.
- History of severe brain injury.
- Presence of implanted metal devices, such as a pacemaker or medication pump.
- Current or past severe psychiatric disorders, such as schizophrenia, bipolar disorder, or major depressive disorder.
- Pregnancy.
- Significant brain abnormalities, such as intracranial space-occupying lesions.
- Family history of epilepsy.
- History of febrile seizures.
- Concurrent use of medications that increase the risk of seizures.
- Sleep disorders during rTMS procedures.
- Skin lesions or trauma at the stimulation site.
- Deemed ineligible by the principal investigator (PI).
- Participation in another clinical trial within the past month.
- Suicidal ideation or suicide attempts within the past year.
Key Trial Info
Start Date :
May 26 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2029
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06974838
Start Date
May 26 2025
End Date
December 31 2029
Last Update
May 16 2025
Active Locations (1)
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1
Chang Gung Memorial Hospital
Taoyuan District, Taiwan