Status:
ENROLLING_BY_INVITATION
Multicenter Prospective Cohort Study of Hypertriglyceridemia Acute Pancreatitis
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Acute Pancreatitis (AP)
Hypertriglyceridemia Acute Pancreatitis
Eligibility:
All Genders
18-80 years
Brief Summary
Hypertriglyceridemia-associated acute pancreatitis (HTG-AP) is the second leading cause in China and is receiving increasing global attention. Research on HTG-AP has been hindered by the heterogeneity...
Eligibility Criteria
Inclusion
- Aged between 18 and 80 years;
- Diagnosed with AP based on at least two of the following criteria (1) acute onset of upper abdominal pain; (2) more than three times the upper limit of the normal range of serum lipase or amylase levels; and (3) typical radiological findings of AP on computed tomography (CT), magnetic resonance imaging, or ultrasonography;
- HTG with serum triglyceride levels \>500 mg/dL (5.65 mmol/L) during the current AP episode or at admission;
- Patients must have good compliance, with the ability and willingness to adhere to study protocols, provide written informed consent, and maintain their current lifestyle during the study period
Exclusion
- History of chronic pancreatitis or pancreatic cancer;
- Severe comorbidities such as malignancy, acute myocardial infarction, or extensive cerebral infarction;
- Prior use of lipid-lowering medications;
- Pregnancy or breastfeeding;
- Lack of signed informed consent.
Key Trial Info
Start Date :
November 13 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2029
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT06976099
Start Date
November 13 2024
End Date
September 1 2029
Last Update
May 16 2025
Active Locations (12)
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1
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China, 100010
2
Xuanwu Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100010
3
Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China, 510515
4
Affiliated Hospital of Zunyi Medical University
Zunyi, Guizhou, China, 563003