Status:
ACTIVE_NOT_RECRUITING
Efficacy of Esketamine Combined With Different General Anesthetics on Quality of Postoperative Recovery
Lead Sponsor:
Northern Jiangsu People's Hospital
Conditions:
Quality of Postoperative Recovery
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
To explore the effect of subanesthetic-dose esketamine combined with different general anesthetic drugs on the quality of postoperative recovery in patients undergoing painless gastrointestinal endosc...
Detailed Description
In this study, we planned to conduct a single-center, prospective, randomized, controlled, double-blind clinical trial to explore the effect of subanesthetic dose esketamine combined with different ge...
Eligibility Criteria
Inclusion
- (1) Aged between 18 and 75 years old (inclusive); (2) ASA (American Society of Anesthesiologists) physical status classification of Class I to III; (3) Body Mass Index (BMI) ranging from 18 to 30 kg/m²; (4) Individuals scheduled to undergo combined gastroscopy and colonoscopy under painless anesthesia; (5) Those with a patent airway and no history of difficult intubation or difficult airway management; (6) Individuals with intact cognitive function, who have provided informed consent, voluntarily participate in this study, and are capable of cooperating to complete data collection.
Exclusion
- （1）A history of unregulated diabetes mellitus, hypertension, or hypotension; （2）Concomitant hyperthyroidism or hypothyroidism; （3）Concomitant psychiatric or neurological disorders; （4）Severe hepatic or renal insufficiency; （5）Concomitant glaucoma, severe hearing or visual impairment that hinders cooperation; （6）Individuals with significant organ dysfunction; （7）Those with allergies to or contraindications for the study drug; （8）Patients with aneurysmal vascular diseases involving the thoracic or abdominal aorta, intracranial arteries, or peripheral arterial vessels; （9）Individuals who are unable to cooperate in completing the Quality of Recovery-15 (QoR-15) questionnaire.
Key Trial Info
Start Date :
March 16 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 15 2025
Estimated Enrollment :
190 Patients enrolled
Trial Details
Trial ID
NCT06976996
Start Date
March 16 2025
End Date
December 15 2025
Last Update
May 16 2025
Active Locations (1)
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1
Northern Jiangsu People's Hospital
Yangzhou, Jiangsu, China, 22500