Status:
RECRUITING
Safety and Tolerability of Low Motoneuron Stimulation Via Transcranial Magnetic Stimulation in Spinal Muscular Atrophy
Lead Sponsor:
Charitable Foundation Children with Spinal Muscular Atrophy
Collaborating Sponsors:
P.V. Voloshyn Institute of Neurology, Psychiatry and Narcology of the National Academy of Medical Sciences of Ukraine
Conditions:
Spinal Muscular Atrophy (SMA)
Eligibility:
All Genders
12+ years
Phase:
NA
Brief Summary
There is a general physiological rule that any organ or system needs some minimal amount of activity to prevent its atrophy or degeneration. Although the relevance of that rule to exercises in neuromu...
Eligibility Criteria
Inclusion
- Subject has a diagnosis of 5q-autosomal recessive SMA confirmed by DNA test.
- Informed consent.
- A minimum score of 1 for Entry Item "A" of the Revised Upper Limb Module (RULM) scale for SMA: "Can use hands to hold pencil or pick up a coin/token or drive a powered chair, use phone key pad"
Exclusion
- Subject has severe joint contractures that would affect ability to perform study measures, determined by the study physician.
- Subject has a deconditioned respiratory system, per the discretion of the physician investigator.
- Subject has behavioral or cognitive problems that preclude participation in the study, in the opinion of the investigator.
Key Trial Info
Start Date :
May 19 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06977269
Start Date
May 19 2025
End Date
January 1 2026
Last Update
June 18 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
P.V. Voloshyn Institute of Neurology, Psychiatry and Narcology of the National Academy of Medical Sciences of Ukraine
Kharkiv, Kharkivs’ka Oblast’, Ukraine, 61068