Status:
COMPLETED
Efficacy of Intraoperative Magnesium Sulphate vs Dexmedetomidine on Emergence Agitation in Pediatric Patients
Lead Sponsor:
Ain Shams University
Conditions:
Magnesium Sulphate
Dexmedetomidine
Eligibility:
All Genders
4-8 years
Phase:
NA
Brief Summary
This study aimed to compare the effectiveness of intraoperative magnesium sulfate versus dexmedetomidine infusions on emergence agitation that follows anesthesia using sevoflurane immediately and afte...
Detailed Description
Emergence agitation (EA) is a postoperative phenomenon that occurs in children after sevoflurane anesthesia, with an occurrence rate of up to 80%. Dexmedetomidine acts on α-2 adrenergic receptors, pr...
Eligibility Criteria
Inclusion
- Age from 4 to 8 years old.
- Both sexes.
- Patients American Society of Anesthesiologists (ASA) Physical Status I to II.
- Duration of surgery: not exceeding two hours
Exclusion
- Legal guardian refusal.
- Neurological abnormalities, such as cerebral palsy.
- Any physical and/or developmental challenge.
- Patients on sedatives, anticonvulsants, or any medications that may alter conscious level in children.
- Coexisting renal or cardiovascular diseases.
Key Trial Info
Start Date :
April 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 10 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06977425
Start Date
April 1 2024
End Date
February 10 2025
Last Update
May 18 2025
Active Locations (1)
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1
Ain shams university
Cairo, Egypt, 11591