Status:
ACTIVE_NOT_RECRUITING
Effect of Non-Selective Beta-Blockers on Outcomes in Cirrhosis Patients After Hospitalization: A Retrospective Cohort Using Target Trial Design
Lead Sponsor:
Samsung Medical Center
Conditions:
Cirrhosis
Decompensated Cirrhosis of Liver
Eligibility:
All Genders
19+ years
Brief Summary
The goal of this observational study is to learn if non-selective beta-blockers (NSBB) improve outcomes in patients with chronic hepatitis B or C who are discharged after hospitalization for acute dec...
Detailed Description
This retrospective cohort study aims to investigate the effects of non-selective beta-blockers (NSBB) on clinical outcomes in patients with chronic hepatitis B or C who were hospitalized for acute dec...
Eligibility Criteria
Inclusion
- Patients with liver cirrhosis and chronic hepatitis B or C
- Hospitalized due to hepatic complications (hepatic encephalopathy, hepatorenal syndrome, ascites, or spontaneous peritonitis) between January 2013 and October 2023
- Age 19 years and older
Exclusion
- History of bradycardia
- History of hypotension
- History of asthma
- History of cancer
- History of heart failure
- History of myocardial infarction
- History of stroke
- History of chronic kidney disease
- History of chronic obstructive pulmonary disease (COPD)
- History of ischemic heart disease
- Esophageal variceal bleeding during index hospitalization
Key Trial Info
Start Date :
January 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2025
Estimated Enrollment :
7725 Patients enrolled
Trial Details
Trial ID
NCT06977685
Start Date
January 1 2013
End Date
December 31 2025
Last Update
May 18 2025
Active Locations (1)
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1
Samsung Medical Center
Seoul, South Korea