Status:
RECRUITING
Impact of Genetic Polymorphisms And DASH Diet On Weight Loss Progression In Climacteric Women With Metabolic Syndrome
Lead Sponsor:
Nutrindo Ideais Research Center
Collaborating Sponsors:
Universidade Federal do Rio de Janeiro
Conditions:
Nutrition
Metabolic Syndrome
Eligibility:
FEMALE
40-60 years
Phase:
NA
Brief Summary
Metabolic syndrome is a multifactorial inflammatory condition that is very prevalent in overweight women with type 2 diabetes. However, there seems to be great benefit in changing lifestyle and dietar...
Detailed Description
Prospective, single-arm, unblinded clinical trial lasting 90 days. The study population will consist of menopausal women aged between 40 and 60 years who are obese (BMI \> 30) and diagnosed with metab...
Eligibility Criteria
Inclusion
- The study population will consist of menopausal women aged between 40 to 60 years old
- Obese (BMI \> 30) with a diagnosis of MS.
- The inclusion criteria are the presence of at least 3 of the 5 criteria\* for MS, which include:
- Abnormal waist circumference values (≥89 cm in women)
- SBP ≥120 mm Hg and DBP ≥80 mm Hg) or diagnosis of hypertension
- Fasting blood glucose equal to or greater than 100 mg/dL or diagnosis of DM2
- HDL-c less than 50 mg/dL in women
- Triglycerides ≥150 mg/dL.
Exclusion
- Patients with a BMI \<25 kg/m2
- The following chronic diseases will not be eligible:
- Active cancer
- Active tuberculosis
- Psychiatric illnesses
- Multiple sclerosis
- Severe nephropathy
- Advanced stages of Paget's disease.
- These chronic conditions could interfere with the results of this study, especially adherence to diet and weight loss. Patients who do not complete all stages of the study, who are not adhering to the intervention or who present any complication that interferes with the results of the study will be excluded from the study.
Key Trial Info
Start Date :
April 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 30 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06978504
Start Date
April 1 2025
End Date
October 30 2025
Last Update
May 18 2025
Active Locations (1)
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1
Nutrindo Ideais Research Center
Rio de Janeiro, Brazil, 22421-000