Status:
RECRUITING
Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia
Lead Sponsor:
Al-Azhar University
Conditions:
Cough
Eligibility:
All Genders
21-60 years
Phase:
PHASE3
Brief Summary
The aim of this prospective randomized controlled double-blinded study is to compare the efficacy of dexmedetomidine, MgSO4 and lidocaine for cough suppression during general anesthetic emergence as r...
Eligibility Criteria
Inclusion
- Aged 21-60 years.
- Both genders.
- Body mass index \< 30 kg/ m2
- American Society of Anesthesiology (ASA) physical status I-II.
- Mallampati score class I or II.
- Patients undergoing surgery under general anesthesia.
Exclusion
- Known allergy to study drugs.
- History of psychiatric illness.
- Patients with major organ diseases.
- Pre-existing neurological deficits.
- Body mass index \>30 kg/m2.
- Active airway infection or history of tracheal and laryngeal surgery.
- Lower esophageal sphincter incompetence (and reflux).
- Increased intracranial and intraocular pressure.
- Use of cough-inducing medications
- Pregnant, and lactating women.
Key Trial Info
Start Date :
June 2 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2026
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT06979141
Start Date
June 2 2025
End Date
August 1 2026
Last Update
June 11 2025
Active Locations (1)
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1
Faculty of Medicine, Al-Azhar university Assiut, Egypt.
Asyut, Egypt, 2091110