Status:
NOT_YET_RECRUITING
Physical Activity Oxidative Stress and Inflammation With Ageing
Lead Sponsor:
Nantes University Hospital
Collaborating Sponsors:
Société KONDREE
Laboratoire PhyMedExp
Conditions:
Inflammation
Oxydative Stress
Eligibility:
All Genders
70-90 years
Brief Summary
Sarcopenia, an age-related decline in muscle function, are thought to be influenced by oxidative stress and low-grade inflammation, resulting in significant muscle mass reduction and altered physical ...
Detailed Description
The POXI-Ageing study aims to explore the relationship between oxidative stress, chronic inflammation, and muscle function in older individuals. The research hypothesizes that these biological factors...
Eligibility Criteria
Inclusion
- Male or female, aged 70 to 90, consulting the Nantes CHU CANGC (Bellier Hospital) and who has an indication for a blood test scheduled as part of routine care within 4 months according to the clinician.
- Clinical Frailty Scale (CFS) score less than or equal to 4 (i.e. threshold for identifying frail elderly people).
Exclusion
- Opposition to participation in the study
- Indication for emergency blood sampling in the city
- Use of a wheelchair or with a proven disability
- Criteria for undernutrition: weight loss of more than 5% in the last month or more than 10% in the last 6 months and/or BMI strictly less than 22 kg/m2.
- Tobacco consumption
- Diabetes
- Any type of active and/or treated cancer less than 5 years old
- Chronic inflammation pathology
- Clinically significant infectious or inflammatory episode ended at least one month ago
- Long-term or last-month corticosteroid therapy
- Antioxidants or trace elements taken in the last 3 months
- Patient not affiliated to a Social Security system
- Patient deprived of liberty by judicial or administrative decision
- Patients under guardianship or trusteeship
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2027
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06980896
Start Date
September 1 2025
End Date
May 1 2027
Last Update
May 20 2025
Active Locations (1)
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1
Dr Anthony Dylis
Nantes, Nantes, France, 44000