Status:
COMPLETED
Effects of Anesthesia Type on Inflammatory Response
Lead Sponsor:
Tokat Gaziosmanpasa University
Conditions:
Spinal Aneshtesia
General Anesthetic
Eligibility:
All Genders
18-75 years
Brief Summary
In total knee arthroplasty, surgical and anesthetic procedures can lead to a significant increase in systemic inflammation. This procedure is frequently performed under either general or spinal anesth...
Eligibility Criteria
Inclusion
- Patients aged 18 to 75 years
- Patients with ASA physical status I or II
- Patients who have underwent total knee arthroplasty under general or spinal anesthesia
Exclusion
- Patients with BMI ≥40 kg/m2
- Patients with ASA physical status ≥III
- Patients with severe cardiopulmonary or metabolic disorders, coagulation disorders or active infection
- Patients with known allergies or chronic steroid use
- Patients with incomplete laboratory data
- Patients who underwent revision total knee arthroplasty
- Patients who required intraoperative conversion from spinal to general anesthesia
- Patients with a history of major trauma and/or emergency surgery
Key Trial Info
Start Date :
January 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 10 2025
Estimated Enrollment :
849 Patients enrolled
Trial Details
Trial ID
NCT06984315
Start Date
January 1 2020
End Date
May 10 2025
Last Update
May 25 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Tokat Gaziosmanpasa University
Tokat Province, Turkey (Türkiye), 60100