Status:

COMPLETED

Evaluation of a Non-cross-linked Hyaluronic Acid Medical Device ("Electri" and "XELA REDERM") for Improving Facial Skin Appearance

Lead Sponsor:

Institute Hyalual GmbH

Conditions:

Appearance of Facial Wrinkles

Aesthetic

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this clinical investigation is to learn whether injectable implants based on non-cross-linked hyaluronic acid (Electri and XELA REDERM) improve the aesthetic appearance of facial skin in a...

Eligibility Criteria

Inclusion

  • Subject agreed to participate in the Investigation and signed the Informed Consent Form.
  • Age over 18 years.
  • The subject is eager to undergo a course of skin redermalization procedures using the medical device(devices) based on non-cross-linked hyaluronic acid in concentrations of 0.55% ("Electri") and 1.1%, 1.8% or 2.2% ("XELA REDERM") (Diaco Biofarmaceutici S. r. l., Italy) in Poland; in concentrations of 1.1%, 1.8% or 2.2% ("XELA REDERM") (Diaco Biofarmaceutici S. r. l., Italy) in Ukraine.
  • Female subject confirm that she is not pregnant or lactating during the study.

Exclusion

  • Infection or inflammation in the implant injection site.
  • Pregnancy, lactation.
  • Subject's intention to undergo procedures involving chemical peels, laser irradiation, botulinum toxin injection or other similar procedures in the injection site within the next 45 days after inclusion in the post-marketing investigation.
  • Subject underwent procedures involving chemical peels, laser irradiation, botulinum toxin injection or other similar procedures in the injection site within 35 days prior to inclusion in the post-marketing investigation.
  • Chronic or acute severe or decompensated visceral diseases.
  • Known hypersensitivity to hyaluronic acid, its metabolites, or to the excipients of the injectable implant.
  • Known hypersensitivity to analgesics.
  • Subject took significant doses of vitamin E, NSAIDs or anticoagulants during the last 7 days.
  • Refusal or suspected inability of the subject to comply with the requirements of the CIP.
  • Subject has difficulty in understanding the language in which the informed consent is written.
  • Any other reason that, in the opinion of the investigator, prevents the subject from participating in the post-marketing investigation.
  • Subject takes participation in other clinical investigation.

Key Trial Info

Start Date :

March 30 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 29 2021

Estimated Enrollment :

77 Patients enrolled

Trial Details

Trial ID

NCT06984432

Start Date

March 30 2021

End Date

October 29 2021

Last Update

June 5 2025

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Provita Sp. z o.o.

Katowice, Poland, 40-611

2

Ośrodek medyczny OSTEOMED s.c.

Krakow, Poland, 30-074

3

Prime Clinic Sp. z o.o.

Warsaw, Poland, 00-342

4

Institute Hyalual LLC

Kyiv, Ukraine, 03151

Evaluation of a Non-cross-linked Hyaluronic Acid Medical Device ("Electri" and "XELA REDERM") for Improving Facial Skin Appearance | DecenTrialz