Status:

NOT_YET_RECRUITING

Human Umbilical Cord-mesenchymal Stem Cells Via Different Transplantation Routes in ESLD

Lead Sponsor:

General Hospital of Shenyang Military Region

Conditions:

End-Stage Liver Diseases

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Stem cells are non-terminal cells that can self renew and replicate through symmetric or asymmetric division, with the potential to differentiate into different types of cells and tissues. Multiple st...

Detailed Description

Thirty-two participants with end-stage liver disease admitted to the Department of Gastroenterology of the General Hospital of Northern Theater Command are expected to be enrolled over a period of 6 m...

Eligibility Criteria

Inclusion

  • 18-80 years old
  • \-
  • End-stage liver disease
  • \-
  • Signed informed consent

Exclusion

  • Tumours of the liver or other organs
  • \-
  • Liver transplantation recipients
  • \-
  • Acute myocardial infarction, acute heart failure, type I and type II respiratory failure, pulmonary embolism, acute cerebral infarction, acute cerebral haemorrhage and other serious cardiopulmonary diseases
  • \-
  • Other diseases that may seriously affect the survival
  • \-
  • Human immunodeficiency syndrome
  • \-
  • Interferon or glucocorticoid therapy within 1 year
  • \-
  • Treated for mental illness
  • \-
  • Participation in other clinical trials within 30 days
  • \-
  • Pregnant or breastfeeding subjects
  • \-
  • Allergic asthma, allergic urticaria, eczema, or a history of multiple drug and food allergies
  • \-
  • Other circumstances that are unsuitable for participation in this study

Key Trial Info

Start Date :

September 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT06984497

Start Date

September 1 2025

End Date

December 1 2027

Last Update

August 24 2025

Active Locations (1)

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General Hospital of Northern Theater Command Recruiting

Shenyang, Liaoning, China, 110840