Status:
ENROLLING_BY_INVITATION
Urgent Panendoscopy in Patients Presenting With Hematochezia
Lead Sponsor:
Mahidol University
Conditions:
Lower Gastrointestinal Bleeding
Small Bowel Bleeding
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Gastrointestinal bleeding is a significant emergency condition requiring prompt diagnosis. Current evidence presents a clinical paradox: urgent colonoscopy (within 24 hours) shows no clear benefit in ...
Detailed Description
Gastrointestinal bleeding is a common emergency condition and an important public health issue, as it impacts hospitalization rates and mortality in the population if not properly diagnosed and treate...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Admission for maroon stool and/or red blood per rectum with or without hemodynamic instability
- Hemodynamic stabilization after initial fluid resuscitation
- Correction of any coagulopathy prior to endoscopy
- Provision of informed consent
Exclusion
- Hematemesis or nasogastric lavage showing coffee ground material/blood
- Persistent hemodynamic instability prior to colonoscopy
- Hospitalization in the preceding 14 days
- Contraindications to endoscopy e.g. severe asthma, cardiac disease
- Uncorrected coagulopathy
- Contraindications to bowel preparation with polyethylene glycol
- Pregnancy
- Inflammatory bowel disease
Key Trial Info
Start Date :
April 9 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2028
Estimated Enrollment :
188 Patients enrolled
Trial Details
Trial ID
NCT06985277
Start Date
April 9 2024
End Date
January 1 2028
Last Update
May 30 2025
Active Locations (1)
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1
Gastroenterology division, Faculty of Medicine, Siriraj Hospital, Mahidol University Bangkok, , Thailand
Bangkok, Bangkok, Thailand, 10700