Status:
ACTIVE_NOT_RECRUITING
ESAN III - Energy Sensing in Depression
Lead Sponsor:
Medical University of Graz
Conditions:
Obesity
Gut Microbiota Modulation
Eligibility:
FEMALE
18-65 years
Phase:
NA
Brief Summary
The purpose of this study is to assess the effects of carotenoids from natural carrot juice on the immune system. Therefore, the study aims to distinguish the effects of natural juices that are rich i...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA
- Socio-demographic criteria:
- Gender: female
- Age: 18-65 years
- Confirmation of study participation:
- Received information on the aims, methods, anticipated benefits, potential risks, and entailed discomforts of the study
- Signed declaration of consent
- Subgroup of depressive patients:
- Diagnosis of depression according to the ICD-10 criteria
- Diagnosis confirmed by an experienced psychiatrist
- Subgroup of normal weight participants:
- • WHO criteria for normal weight (Body Mass Index \[BMI\] 18.5-24.99 kg/m²)
- Subgroup of obese participants:
- • WHO criteria for obesity (BMI \> 30.0 kg/m²)
- EXCLUSION CRITERIA
- Formal criteria:
- • Lack of informed consent
- Health criteria:
- Alcohol or drug abuse
- Acute or chronic diseases or infections (including cancer, fever, pneumological or renal disorders, cardiovascular disease, hematopoietic disorders)
- Digestive disorders (including fructose intolerance, inflammatory bowel disease, irritable bowel syndrome)
- Treatment that may have influenced the microbiome (including antibiotic or antifungal treatment within the previous two months, and daily or irregular intake of prebiotics or probiotics within the previous two months; the intake of yogurt and dairy products is permitted)
- History of gastrointestinal surgery (other than appendectomy)
- Psychiatric disorders (schizophrenia, dementia, bipolar disorder)
- Pregnancy or breastfeeding
Exclusion
Key Trial Info
Start Date :
March 13 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2026
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06985381
Start Date
March 13 2024
End Date
January 1 2026
Last Update
June 27 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Medical Universtiy of Graz
Graz, Styria, Austria, 8010