Status:
RECRUITING
Virtual Contexts for Affective Modulation
Lead Sponsor:
Trustees of Dartmouth College
Conditions:
Pain Control
Anxiety
Eligibility:
All Genders
18-55 years
Phase:
NA
Brief Summary
This study investigates how spatial context and perceived controllability modulate pain, affective states such as anxiety, and motivated behavior. The study examines how control over pain and threat-r...
Detailed Description
The study investigates how perceived controllability and threat-related spatial contexts influence pain perception, affective state, autonomic responses, and behavior. Specifically, it aims to dissect...
Eligibility Criteria
Inclusion
- No self-reported current or history of depression, bipolar disorder, or other psychiatric diagnosis
- No self-reported current seizure disorder (i.e., seizure within past 10 years), or history of stroke or other major neurological diagnosis
- No self-reported current chronic pain, or acute pain within three months of the study period
- No current migraine disorder (i.e., 15 headache days or more in 1 month)
- No use of central nervous system-effective medication or other medication for neurological/psychiatric treatment
- No self-reported substance abuse within the last six months
- No contraindication to MRI (e.g., pregnancy, claustrophobia, pacemakers, ear/cochlear implants, shrapnel injuries, clips, or other ferromagnetic/electrical objects/devices, diagnosed brain abnormality such as tumor, or skin lesions on the scalp.)
- No contraindications for induced pain (e.g., no heart disease, high blood pressure, heart surgery, heart problems of any kind, severe asthma, respiratory problems of any kind, fibromyalgia, Raynaud's Syndrome or Disease, chronic pain, diabetes)
- Participants must be capable of performing experimental tasks (e.g., are able to read), are fluent or native speakers of English
- Participants must be able to tolerate the maximum level of thermal pain stimuli (for thermal stimuli)
Exclusion
Key Trial Info
Start Date :
October 28 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 15 2029
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06986122
Start Date
October 28 2025
End Date
June 15 2029
Last Update
October 31 2025
Active Locations (1)
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1
Dartmouth College
Hanover, New Hampshire, United States, 03755