Status:
NOT_YET_RECRUITING
Radiation-induced Toxicity of the Heart
Lead Sponsor:
Technische Universität Dresden
Conditions:
Non-small Cell Lung Cancer
Esophageal Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Late side effects in radio(chemo)therapy \[R(CH)T\] pose a critical limitation to patients' overall survival and quality of life. Even though toxicities of the heart are highly relevant for patients w...
Detailed Description
79 patients with non-small cell lung or esophageal cancer, and 246 patients with breast cancer to be treated with curative R(CH)T at the University Hospital Carl Gustav Carus Dresden, Germany will be ...
Eligibility Criteria
Inclusion
- Patients 18 years old or older
- Patient's consent and written consent is available
- Patients with the non-small cell lung cancer or esophageal cancer or breast cancer who have an indication for intended curative radio(chemo)therapy (in the case of breast cancer inclusion of female patients only)
Exclusion
- Patients who are not capable of giving consent
- Pregnant women
- Patients with contraindications for MRI examinations (pacemakers, defibrillators, neurostimulators, aneurysm clips, cochlear implants, permanent make-up, metal splinters or osseosynthetic implants)
- Patients with insufficient kidney function (glomerular filtration rate (GFR) of less than 30 ml/min)
- Patients with the aforementioned tumour entities for whom a palliative indication exists
Key Trial Info
Start Date :
August 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2039
Estimated Enrollment :
325 Patients enrolled
Trial Details
Trial ID
NCT06986291
Start Date
August 1 2025
End Date
December 1 2039
Last Update
May 29 2025
Active Locations (1)
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1
University of Technology, University Hospital Carl Gustav Carus, Department of Radiation Therapy and Radiation Oncology
Dresden, Germany, Germany, 01304