Status:

NOT_YET_RECRUITING

Reducing Pain in Complex Regional Pain Syndrome Using Personalized Brain Stimulation: A Feasibility Study

Lead Sponsor:

McMaster University

Collaborating Sponsors:

Michael G. DeGroote Institute for Pain Research and Care (IPRC)

Conditions:

Complex Regional Pain Syndrome (CRPS)

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

This research study looks at the feasibility of using a new treatment, noninvasively activating the brain through repetitive transcranial magnetic stimulation (rTMS) to treat pain symptoms of complex ...

Detailed Description

Complex regional pain syndrome (CRPS) is a chronic pain condition that is debilitating and dramatically decreases the quality of life. CRPS is characterized by a constellation of sensory, motor, and a...

Eligibility Criteria

Inclusion

  • Diagnosis of CRPS Type 1 affecting the upper or lower limb using the revised Budapest criteria
  • History of CRPS of at least 3 months since the start of symptoms or diagnosis

Exclusion

  • CRPS diagnosis greater than 3 years to avoid patients with chronic CRPS who may not respond to interventions
  • Contraindications to transcranial magnetic stimulation (TMS)
  • Known psychological diagnosis affecting comprehension
  • Prior experience with TMS
  • Inability to participate in the study

Key Trial Info

Start Date :

July 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2026

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT06987747

Start Date

July 1 2025

End Date

February 1 2026

Last Update

May 23 2025

Active Locations (1)

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1

McMaster University

Hamilton, Ontario, Canada, L8S 4L8