Status:

NOT_YET_RECRUITING

Clinical Outcomes and Ejaculatory Function in BPO Patients Treated With Silodosin

Lead Sponsor:

Marmara University

Conditions:

Benign Prostate Obstruction (BPO)

Lower Urinary Tract Symptom

Eligibility:

MALE

40+ years

Brief Summary

This observational study aims to evaluate the relationship between silodosin-induced anejaculation and clinical outcomes in male patients with benign prostatic obstruction (BPO). Silodosin is a common...

Detailed Description

This is a observational study designed to investigate the association between silodosin-induced anejaculation and clinical outcomes in patients diagnosed with benign prostatic obstruction (BPO). Silod...

Eligibility Criteria

Inclusion

  • Male patients aged 40 years or older
  • Diagnosed with lower urinary tract symptoms (LUTS) due to benign prostatic obstruction (BPO)
  • Initiating silodosin 8 mg/day therapy for the first time
  • Able to complete IPSS and IIEF-5 questionnaires
  • Willing and able to provide written informed consent

Exclusion

  • History of prior treatment with silodosin or other α-blockers in the last 3 months
  • Known neurogenic bladder or history of neurological disease affecting voiding
  • History of prostate surgery or pelvic radiation
  • Diagnosed prostate or bladder malignancy
  • Use of medications affecting sexual function (e.g., PDE5 inhibitors) within the last month
  • Severe cardiovascular, hepatic, or renal comorbidities
  • Cognitive impairment preventing informed consent or questionnaire completion

Key Trial Info

Start Date :

June 15 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 12 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06989515

Start Date

June 15 2025

End Date

June 12 2026

Last Update

June 5 2025

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