Status:
NOT_YET_RECRUITING
Lynch Syndrome in Colorectal Cancer Surgery
Lead Sponsor:
Izmir Ataturk Training and Research Hospital
Conditions:
Colo-rectal Cancer
Hereditary Diseases
Eligibility:
All Genders
18+ years
Brief Summary
Study Design (Material and Methods) This is a multicentre, prospective cohort and audit study conducted in Türkiye. The study aims to evaluate the incidence of Lynch syndrome among patients who under...
Detailed Description
Study Design (Material and Methods) This is a multicentre, prospective cohort and audit study conducted in Türkiye. The study aims to evaluate the incidence of Lynch syndrome among patients who under...
Eligibility Criteria
Inclusion
- Age 18 years or older
- Histologically confirmed diagnosis of colorectal adenocarcinoma
- Undergoing surgical resection at one of the participating general surgery departments
- Availability of formalin-fixed, paraffin-embedded (FFPE) tumor tissue for MMR analysis
- Consent to participate in the study and undergo genetic testing if indicated
Exclusion
- Age below 18 years
- Diagnosis other than colorectal adenocarcinoma
- Incomplete or unavailable postoperative pathology results
- Inadequate tissue samples for IHC analysis
- Patients who decline participation in the study at any point
- Patients who do not attend or refuse referral to genetic counseling after pathology results
Key Trial Info
Start Date :
July 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2026
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT06990633
Start Date
July 1 2025
End Date
August 1 2026
Last Update
May 25 2025
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.