Status:
RECRUITING
Concentration of n-3 PUFA Monohydroxylated Derivatives in Adults With Obesity After n-3 PUFA Supplementation.
Lead Sponsor:
University of North Carolina, Chapel Hill
Collaborating Sponsors:
Metagenics, Inc.
Conditions:
Obesity
Eligibility:
All Genders
45-60 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn if daily supplementation with SPM Active® can increase omega 3 polyunsaturated fatty acid derivatives and improve well-being in adults with obesity. The mai...
Detailed Description
Purpose: This study aims to explore the effects of 'SPM Active®,' an omega-3 polyunsaturated fatty acid (n-3 PUFA) dietary supplement, on male adults with obesity. The supplement specifically targets ...
Eligibility Criteria
Inclusion
- adults, ages 45-60 years
- Body mass index (BMI) between 30 and 40 kg/m\^2
- Any race or ethnicity
Exclusion
- Age \< 45 years or \> 60 years
- pregnant or breastfeeding women
- BMI \< 30 kg/m\^2 or \> 40 kg/m\^2
- Diagnosed type 1 or type 2 diabetes
- Active autoimmune disease, liver disease, coagulopathy, or hypothyroidism
- Known allergy to fish or shellfish
- Current use of any of the following medications: asthma controller therapies, anticoagulants, estrogen or testosterone, daily aspirin or NSAIDs.
- Inability to give informed consent
- Receiving immunomodulatory or immunosuppressant therapy
- Known active malignancy or undergoing treatment for malignancy
- Use of n-3 PUFA supplements or high consumption of fatty fish (\> 2 servings/week) within 3 months prior to enrollment.
Key Trial Info
Start Date :
June 2 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT06991296
Start Date
June 2 2025
End Date
December 1 2025
Last Update
October 21 2025
Active Locations (1)
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1
UNC Nutrition Research Institute
Kannapolis, North Carolina, United States, 28081