Status:

NOT_YET_RECRUITING

Immunological Impact of a Post Cell Therapy Treatment With FLT3 Inhibitors

Lead Sponsor:

Centre Hospitalier Universitaire de Nice

Conditions:

Hematological Malignancies

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Allogeneic hematopoietic stem cell transplantation (aHSCT) is the only curative option for many hematological maligancies. The main cause of death following HSCT is the relapse of the original disease...

Eligibility Criteria

Inclusion

  • Patient \> 18y/o
  • Patient who received an allogeneic stem cell transplantation for an acute myeloid leukemia and who will receive gilteritinib as post transplantation maintenance
  • Matched related, matched unrelated, mismatched unrelated and haploidentical donors

Exclusion

  • Minors
  • Pregnant women
  • Patient under 'tutelle', 'curatelle' or in prison
  • Patient who has been treated for a solid tumor in the past 2 years
  • Known human immunodeficiency virus (HIV) infection or HIV-related malignancy
  • Clinically active hepatitis B or hepatitis C infection
  • Known allergy or hypersensitivity to gilteritinib

Key Trial Info

Start Date :

August 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2028

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT06992934

Start Date

August 1 2025

End Date

August 1 2028

Last Update

August 3 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

CHU de NICE

Nice, France