Status:
NOT_YET_RECRUITING
Comparison of Haloperidol and Dexmedetomidine for Delirium and Agitation in ICU Patients With Traumatic Brain Injury
Lead Sponsor:
Benha University
Conditions:
Traumatic Brain Injury
Delirium
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Traumatic brain injury is a serious and common medical condition that often requires admission to the intensive care unit and the use of mechanical ventilation. One of the most frequent and challengin...
Eligibility Criteria
Inclusion
- Adults aged 18 years or older
- Confirmed diagnosis of traumatic brain injury
- Admission to the intensive care unit
- Currently receiving mechanical ventilation
- Richmond Agitation-Sedation Scale score between -5 and +4
- At least 48 hours have passed since ICU admission
Exclusion
- Pre-existing neurological or psychiatric disorders (e.g., schizophrenia, bipolar disorder)
- Known allergy or contraindication to haloperidol or dexmedetomidine
- Significant hepatic or renal dysfunction
- Pregnant or breastfeeding women
- History of prolonged QT interval or other cardiac arrhythmias
- Use of long-term antipsychotic or sedative medications before ICU admission
Key Trial Info
Start Date :
June 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 15 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06993194
Start Date
June 15 2025
End Date
June 15 2026
Last Update
May 28 2025
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.