Status:

NOT_YET_RECRUITING

Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Recurrent Aphthous Stomatitis

Lead Sponsor:

Cairo University

Conditions:

Recurrent Aphthous Stomatitis

Eligibility:

All Genders

18-60 years

Phase:

PHASE2

Brief Summary

Bromelain, a natural product, exhibits anti-inflammatory, immunomodulatory, and wound-healing properties. However, its efficacy in treating oral mucosal ulcers remains unexplored. This study aims to e...

Eligibility Criteria

Inclusion

  • Adults aged 18-60 years.
  • Diagnosed with RAS.
  • Onset of ulcer within the last 48 hours.
  • Willingness to participate and provide informed consent.

Exclusion

  • History of hematological deficiencies, GIT disorders, Behcet's disease and major systemic diseases.
  • Pregnant or breastfeeding patients.
  • Previous treatment for the current ulcer episode.

Key Trial Info

Start Date :

June 15 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 15 2026

Estimated Enrollment :

63 Patients enrolled

Trial Details

Trial ID

NCT06993337

Start Date

June 15 2025

End Date

June 15 2026

Last Update

May 28 2025

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