Status:

RECRUITING

Analysis of Safety and Tissue Interaction of Injectable and Energy-based Biosmulators

Lead Sponsor:

Universitätsklinikum Hamburg-Eppendorf

Conditions:

This Study Aims to Evaluate the Safety Profile and Tissue Changes After Biostimulatory Treatments to the Face in Healthy Volunteers

Eligibility:

All Genders

30+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to analyse tissue changes in the pre-auricular region after injectable (Poly-L-Lactic-Acid/Calcium-Hydroxylapatit/ and energy-based (Radiofrequency Microneedling) bi...

Detailed Description

Patients undergoing biostimulatory treatments will be invited to participate in this study involving photographic evaluations and ultrasound imaging. Following detailed oral and written explanations, ...

Eligibility Criteria

Inclusion

  • Men and women aged 30 years and older
  • Good general health, no relevant pre-existing conditions
  • Patients planning to undergo CaHa, PLLA, or RFMN treatment as part of routine care due to skin laxity or volume loss
  • Cognitive ability and willingness to provide informed consent
  • Willingness and ability to attend follow-up visits

Exclusion

  • Age under 30 years
  • Pregnant or breastfeeding individuals
  • Significant open wounds or lesions in the treatment area
  • Metallic implants in the treatment area
  • Psychiatric disorders (psychosis, body dysmorphic disorders)
  • Missing informed consent and/or data privacy declarations

Key Trial Info

Start Date :

March 22 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 22 2026

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06993558

Start Date

March 22 2025

End Date

September 22 2026

Last Update

May 29 2025

Active Locations (1)

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1

University Hospital Hamburg Eppendorf

Hamburg, Hamburg, Germany, 20246