Status:

RECRUITING

A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes

Lead Sponsor:

Eli Lilly and Company

Conditions:

Obesity

Overweight

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this Master Protocol is to support two studies to see how well and how safely orforglipron works compared to placebo in participants who have obesity or overweight with or without type ...

Eligibility Criteria

Inclusion

  • There are no specific eligibility criteria for the Master Protocol.
  • See study GZP1 for eligibility criteria relevant to participants with obesity and overweight without type 2 diabetes
  • See study GZP2 for eligibility criteria relevant to participants with type 2 diabetes

Exclusion

    Key Trial Info

    Start Date :

    May 15 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    August 1 2027

    Estimated Enrollment :

    1200 Patients enrolled

    Trial Details

    Trial ID

    NCT06993792

    Start Date

    May 15 2025

    End Date

    August 1 2027

    Last Update

    December 17 2025

    Active Locations (80)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 20 (80 locations)

    1

    Clinical Research Institute of Arizona (CRI) - Sun City West

    Sun City West, Arizona, United States, 85375

    2

    Novak Clinical Research - Tucson - North La Cholla Boulevard

    Tucson, Arizona, United States, 85741

    3

    Norcal Endocrinology & Internal Medicine

    San Ramon, California, United States, 94583

    4

    Southern California Clinical Research

    Santa Ana, California, United States, 92701