Status:
RECRUITING
Investigation of the Correlation Between Polyamine Levels and Their Key Enzymatic Activities in Association With Inflammatory Bowel Disease Progression
Lead Sponsor:
Xijing Hospital
Conditions:
Inflammatory Bowel Diseases
Colitis, Ulcerative
Eligibility:
All Genders
18-65 years
Brief Summary
Inflammatory Bowel Disease (IBD), encompassing Ulcerative Colitis (UC) and Crohn's Disease (CD), significantly impairs patients' quality of life. Current monitoring of disease activity primarily relie...
Detailed Description
According to the inclusion and exclusion criteria, 91 patients with IBD diagnosed in the Department of Gastroenterology, the First Affiliated Hospital of Air Force Medical University from November 202...
Eligibility Criteria
Inclusion
- Age between 18 and 65 years;
- Diagnosed with inflammatory (IBD) according to the Chinese Guidelines for the Diagnosis and Treatment of Ulcerative Colitis (2023, Xi'an) and the Chinese Guidelines for the Diagnosis and Treatment of Crohn's Disease (2023, Guangzhou);
- Complete medical records available and written informed consent obtained from the participant.
Exclusion
- Presence of other metabolic disorders;
- History of malignant tumors, severe organ dysfunction, or other severe systemic diseases affecting major organs, or hematological disorders;
- Diagnosis of influenza, bacterial dysentery, or other infectious diseases within the past 2 weeks;
- Presence of other diseases that may interfere with polyamine metabolism;
- Use of antibiotics or probiotics within 8 weeks prior to the start of the study.
Key Trial Info
Start Date :
January 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
146 Patients enrolled
Trial Details
Trial ID
NCT06995170
Start Date
January 1 2025
End Date
December 1 2025
Last Update
May 29 2025
Active Locations (1)
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1
Xijing Hospital
Xi'an, Shaanxi, China, 710032