Status:

NOT_YET_RECRUITING

Breast Cancer and Chemobrain : Effects of Photobiomodulation on the Improvement of Perceived Cognitive Impairment

Lead Sponsor:

Centre Hospitalier de Valenciennes

Conditions:

Oncology

Support Care

Eligibility:

FEMALE

Phase:

NA

Brief Summary

Breast cancer is one of the most common cancers in metropolitan France, with over 60,000 new cases in 2023. Mostly a female cancer, it can affect a young population, with around 20% of breast cancers ...

Eligibility Criteria

Inclusion

  • Women aged 18 and over
  • Having completed chemotherapy (intravenous) for breast cancer (any stage) less than 12 months prior to inclusion
  • Having a perceived cognitive complaint that appeared during or after (\< 3 months) chemotherapy treatments (no restriction on the care protocol used) and confirmed by a FACT-Cog score compatible with a subjective cognitive disorder (score \< 117 for patients aged 18 to 49; score \< 113 for patients aged 50 to 69; score \<105 for patients aged 70 and over)
  • Patient eligible for photobiomodulation sessions
  • Patient with sufficient command of the French language to complete the study questionnaries
  • Patient having given written consent to participate in the trial
  • Socially insured patient
  • Patient willing to comply with all study procedures and duration

Exclusion

  • Known cognitive disorders prior to chemotherapy treatment
  • Patients with psychiatric or psychobehavioral disorders incompatible with photobiomodulation sessions
  • Patients who, in the 12 months prior to inclusion or at the time of inclusion, have already received photobiomodulation treatment involving "whole body" therapy (photobiomodulation in a phototherapy booth).
  • Patient having previously received photobiomodulation with cortical stimulation (panel or helmet) with no time limit.
  • Patient taking or having received capecitabine
  • Patients taking part in a protocol involving a drug likely to affect cognitive performance (on the investigator's advice).
  • Patients suffering from claustrophobia
  • Patient unable to read and/or unable to complete a questionnaire, in the opinion of the investigator

Key Trial Info

Start Date :

June 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06995443

Start Date

June 1 2025

End Date

December 1 2027

Last Update

May 29 2025

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Breast Cancer and Chemobrain : Effects of Photobiomodulation on the Improvement of Perceived Cognitive Impairment | DecenTrialz