Status:
NOT_YET_RECRUITING
Multivariate Analysis and Prediction of Hypertensive Disorder Complicating Pregnancy and Its Related Mechanism
Lead Sponsor:
First Affiliated Hospital of Harbin Medical University
Conditions:
Hypertensive Disorder Complicating Pregnancy
Eligibility:
FEMALE
20-45 years
Brief Summary
Hypertensive disorder complicating pregnancy (HDP) is a unique disease during pregnancy, accounting for about 5.2% \~ 8.2% of pregnant women in the world, which seriously threatens the health and life...
Eligibility Criteria
Inclusion
- singleton pregnancy;
- Those who meet the relevant diagnostic criteria in Guidelines for the Diagnosis and Treatment of Hypertensive Disorders during Pregnancy (2020).
Exclusion
- Patients with severe cardiovascular diseases, blood system diseases and organ damage before pregnancy;
- Persons with severe mental illness;
- Pregnant women who gave birth to children with birth defects in pregnancy outcome;
- Patients who are not suitable for taking blood samples, such as anemia;
- Patients who are in an emergency during operation and are difficult to take tissue samples;
- Patients with chronic hypertension complicated with pregnancy;
- History of taking antibiotics, immunotoxic drugs, hormone antagonists and large doses of probiotics within 3 months;
- Patients who refused to participate in the trial.
Key Trial Info
Start Date :
May 25 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 25 2028
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT06995456
Start Date
May 25 2025
End Date
May 25 2028
Last Update
May 29 2025
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