Status:
ENROLLING_BY_INVITATION
Application of Bacterial DNA Quantitative Detection in Diagnosis of SBP in Cirrhosis: A Multi Center Diagnostic Experiment
Lead Sponsor:
Beijing YouAn Hospital
Conditions:
Cirrhosis
Ascites
Eligibility:
All Genders
18+ years
Brief Summary
Background and Significance: Spontaneous bacterial peritonitis (SBP) is a common and life-threatening complication in patients with liver cirrhosis, characterized by high incidence and mortality. The...
Eligibility Criteria
Inclusion
- Age ≥ 18 years, no restriction on gender.
- Diagnosis of liver cirrhosis based on imaging, biochemical, or hematological evidence of impaired hepatic synthetic function or portal hypertension, or histologically confirmed cirrhosis, regardless of etiology.
- Diagnosis of ascites according to the 2023 Chinese Clinical Guidelines for the Diagnosis and Treatment of Cirrhotic Ascites and Related Complications.
Exclusion
- Patients with confirmed infections in other tissues or organs.
- Ascites caused by non-hepatic etiologies, such as renal or cardiac ascites.
- Pregnant individuals, intravenous drug users, or HIV-infected individuals.
- Patients with uncontrolled hepatocellular carcinoma or other systemic malignancies.
- Patients who have previously undergone organ transplantation.
- Patients currently receiving glucocorticoids or other immunosuppressive therapies.
Key Trial Info
Start Date :
April 2 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
700 Patients enrolled
Trial Details
Trial ID
NCT06995846
Start Date
April 2 2024
End Date
June 30 2026
Last Update
May 30 2025
Active Locations (1)
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1
No. 8 You An Men Wai Street, Fengtai District, Beijing 100069, China
Beijing, China