Status:

ENROLLING_BY_INVITATION

Liquid BiOpsy, Lung and Colon Cancer in AndaluciA

Lead Sponsor:

Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental

Collaborating Sponsors:

Tempus AI

Conditions:

Non Small Cell Lung Cancer (NSCLC)

Colorectal Cancer (CRC)

Eligibility:

All Genders

18+ years

Brief Summary

The objective of the LOLA Project is to analyse the impact of adopting xF liquid biopsy panel, in the real world of the Andalusian Health Public System in terms of impact on clinical practice and cost...

Eligibility Criteria

Inclusion

  • General criteria:
  • More than 18 years old
  • Both genders
  • Ability to provide written informed consent
  • Specific criteria:
  • NSCLC
  • Patients diagnosed with the 8th Edition of the Tumor, Node, Metastasis (TNM) staging system for Lung Cancer approved by International Association for the Study of Lung Cancer (IASLC) and the American Joint Committee on Cancer (AJCC): IV (Any T, Any N, M1a-c)
  • Histologically confirmed NSCLC (adenocarcinoma)
  • Performance status of 0-2 (ECOG PS) ○ Estimated life expectancy ≥3 months
  • Treatment naïve patients (chemotherapy, immunotherapy, targeted therapy, radiotherapy).
  • Smokers or Non-Smokers
  • CRC
  • Patients diagnosed with the Tumor, Node, Metastasis (TNM) staging system for Colorectal Cancer approved by the American Joint Committee on Cancer (AJCC): IV (Any T, Any N, M1a-c)
  • Histologically confirmed CRC (adenocarcinoma)
  • Performance status of 0-2 (ECOG PS)
  • Estimated life expectancy ≥3 months
  • Treatment naïve patients (chemotherapy, immunotherapy, targeted therapy, radiotherapy).

Exclusion

  • General: History of any other cancer within the previous 5 years, except non-melanoma skin cancer
  • General: Absence of Informed consent. \> Pregnant or nursing women. \> Small cell lung cancer.

Key Trial Info

Start Date :

August 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 30 2026

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT06997458

Start Date

August 1 2024

End Date

July 30 2026

Last Update

May 30 2025

Active Locations (1)

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Centre for Genomics and Oncological Research - Pfizer - University of Granada - Andalusian Regional Government (GENyO)

Granada, Andalusia, Spain, 18016