Status:
COMPLETED
Clinical Efficacy of Local Delivery of Minocycline and Hyaluronan Gel to Treat Periodontitis in Diabetic Patients
Lead Sponsor:
Kafrelsheikh University
Conditions:
Periodontitis and Diabetes
Periodontitis
Eligibility:
All Genders
30-60 years
Phase:
PHASE1
Brief Summary
The goal of this clinical trial is to investigate the local delivery of minocycline gel 2% and 0.2% hyaluronan gel to treat periodontitis in diabetic patients as adjunctive to subgingival instrumentat...
Detailed Description
The aim of the present study was to evaluate the clinical and microbial efficacy of local delivery of minocycline gel 2% and 0.2% hyaluronan gel (Gengigel) as an adjunctive therapy to SRP compared wit...
Eligibility Criteria
Inclusion
- Patients with stage II, grade B periodontitis (Attachment loss 3-4 mm and probing pocket depth ≤ 5mm) in both sides.
- Adult controlled diabetic patients (Glycosylated hemoglobin (HbA1C) in controlled diabetics ≤7%)
- Patients who can maintain good oral hygiene
Exclusion
- History of systemic diseases other than type II diabetes
- Smoking
- Pregnant or lactating women
- Previous treatment of periodontal diseases in the last six months (People who take anti-inflammatory drugs, antibiotics, or vitamins within the previous 6 month).
- People who use mouth washes regularly ·
- Participation in other clinical trials.
Key Trial Info
Start Date :
May 20 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06997731
Start Date
May 20 2023
End Date
February 1 2025
Last Update
May 30 2025
Active Locations (1)
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1
Enas Elgendy
Tanta, Gharbia Governorate, Egypt