Status:
NOT_YET_RECRUITING
Association Between Grade(B/C)of Stage III and IV Periodontitis and High Sensitivity C Reactive Protein Level in Serum and Oral Rinse Sample
Lead Sponsor:
Postgraduate Institute of Dental Sciences Rohtak
Conditions:
hsCRP
Eligibility:
All Genders
18-50 years
Brief Summary
According to 2017 World Workshop of Periodontology , the level of high sensitivity C reactive protein has been assumed to increase according to the grade of periodontitis, however, specific evidence r...
Detailed Description
According to 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions , the level of high sensitivity c reactive protein has been assumed to increase according...
Eligibility Criteria
Inclusion
- Patients in the age group of (18-50 years)
- Presence of ≥ 20 natural teeth
- Ability and willingness to give written informed consent
- Patients belonging to 3 groups -periodontally healthy, stage III and stage IV grade B periodontitis, and stage III and stage IV grade C periodontitis .
Exclusion
- • Patients with chronic inflammatory disease such as nephrotic syndrome, chronic renal failure, significant cardiovascular disease, established type 1 or type 2 diabetes mellitus, or active cancer within the past 5 years
- Smokers and alcoholics
- Pregnant females
- Presence of xerostomia
- Patients undergoing radiotherapy
- Having received professional periodontal treatment within the previous 6 months
- Having received antibiotic medication 3 months prior to study
- Periapical pathology or other oral inflammatory conditions
- Cognitive disability (interfering with ability to give sample)
Key Trial Info
Start Date :
June 25 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 25 2026
Estimated Enrollment :
87 Patients enrolled
Trial Details
Trial ID
NCT06997770
Start Date
June 25 2025
End Date
August 25 2026
Last Update
May 30 2025
Active Locations (1)
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1
PGIDS
Rohtak, Haryana, India, 124001