Status:

NOT_YET_RECRUITING

REGEND001 Autologous Basal Layer Stem Cell Transplantation for Interstitial Lung Disease (ILD): A Translational Application Study

Lead Sponsor:

Ruijin Hospital

Conditions:

Interstitial Lung Disease (ILD)

Eligibility:

All Genders

40-75 years

Phase:

PHASE1

Brief Summary

This clinical trial evaluates the safety and efficacy of REGEND001, an autologous bronchial basal layer stem cell therapy, in patients with interstitial lung disease (ILD). The treatment involves harv...

Eligibility Criteria

Inclusion

  • Age 40-75 years.
  • Confirmed diagnosis of ILD (e.g., IPF, connective tissue disease-associated ILD).
  • DLCO ≥30% and \<80% predicted.

Exclusion

  • Pregnancy, lactation, or plans for pregnancy within 1 year.
  • Active malignancy or history of malignancy.
  • Positive serology for HIV, HBV, HCV, or syphilis.

Key Trial Info

Start Date :

June 30 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT06998706

Start Date

June 30 2025

End Date

June 30 2026

Last Update

May 31 2025

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